The Endocannabinoid System

The Endocannabinoid System

Our budtender Kiki is starting a new audio series where she’ll talk about cannabis and explain the science, culture, and history behind it. The first segment of her series covers the endocannabinoid system.

For this episode the topic is: The Endocannabinoid System

If we break it down, the prefix “endo,” means “made in the body.”

The endocannabinoid system helps regulate appetite, mood, memory, pain and more.

Your endocannabinoid system, or ECS, was discovered by a professor of medical chemistry at Hebrew University by the name of Dr. Raphael Mechoulam.

Our body naturally produces endocannabinoids: The two main endocannabinoids created by the body are anandamide, or AEA, and arachidonylglycerol, or 2-AG. And these endocannabinoids make up just 1 of the 3 parts that make up the ECS.

The endocannabinoid receptors CB1 & CB2 are the next major pieces of the system.

The 3rd function of this system deals with endocannabinoid-moderating enzymes.

Endocannabinoids are lipids that interact with the nervous system to make specific changes happen in the body. Endocannabinoids attach onto individual endocannabinoid receptors to spark that change in the nervous system. All mammals produce endocannabinoids that bind to endocannabinoid receptors.

Now, CB1 resides in the brain and CB2’s in the immune system. Some benefits that come with activating the CB1 receptor include: relieving depression, lowering intestinal inflammation, lowering anxiety and more.

Cannabinoids and the ECS are what helps keep your entire body in homeostasis, or balance. The ECS is the largest neurotransmitter in the body & endocannabinoid receptors are found in the most vital organs and glands.

When your ECS is out of balance research has shown that there is a direct correlation between an ECS deficiency and medical conditions like fibromyalgia, IBS, migraines, mood imbalances, chronic pain, and muscle spasms.

Cannabis is a major key to our endocannabinoid system! Medicating with the right doses, cannabinoids and terpene synergies can really help the body achieve homeostasis! The more you know!

Well, look out for more segments about cannabis brought to you by Kiki at Silver State Relief. If you see her let her know what you’d like her to talk about next. Happy medicating!

Keep out of reach of children. For use of 21 years and older.